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From https://www.macissues.com/2015/06/22/how-to-fully-reset-safari-on-your-mac/
Remove Safari’s configuration folder:
- Open the Go menu in the OS X Finder
- Hold the Option key and choose the Library option that appears
- Move the “Safari” folder in here to your desktop
Remove Safari’s window state:
- Open the Library > Saved Application State folder
- Locate the “com.apple.Safari.savedState” folder
- Move this folder to the trash
Remove Safari’s application caches:
- Open the Library > Caches folder
- Locate all folders that begin with “com.apple.Safari”
- Move these folders to the trash.
Remove Safari Cookies configurations:
- Open the Library > Cookies folder
- Remove the file called “com.apple.Safari.SafeBrowsing.binarycookies”
Remove Safari’s preferences:
- Open the Library > Preferences folder
- Remove any file that begins with “com.apple.Safari”
Remove user plug-ins:
- Go to the Library > Internet Plug-Ins folder
- Move all items from this folder to your Desktop (or elsewhere)